Medicine | Pharmacy | Chemistry


What is Active Pharmaceutical Ingredient (API)

Posted October 2, 2016 by Matt in Uncategorized

Active Pharmaceutical Ingredient(API) is the portion of any drug that is active. Some drugs have more

than one API and the reaction of different drugs differ depending on the administered dosage. A drug is

made up of two components: one is the actual API which forms the basic ingredient and the other is the

substance inside the drug which is known as an excipient. The excipient is the vehicle that carries the

active ingredient and is the liquid in syrups.

Recipients are inactive whereas the active pharmaceutical ingredients are the substances that cause the

drug to react in the desired way. The active ingredient in a drug ought to be of the right quality as it

directly affects the drug’s safety and efficacy. Where the active ingredient is contaminated or poorly

manufactured, the consequences can have serious health outcomes and could even be fatal.

The methods of standardizing the API strength varies depending on the brand where different

manufacturers may adopt different standards for evaluating the strength of the API.

The process of manufacturing Active Pharmaceutical ingredients includes fermentation, chemical

synthesis, and isolation of the ingredients from natural sources among others. The FDA has set standards

relating to documentation, storage and regulatory compliance of APIs. When getting APIs from the

manufacturer ensure that they are labelled, packaged and produced based on the FDA standards.

Most patients are unable to understand the active pharmaceutical ingredient in the drug and may not even

be aware of it. When on multiple medications, the different active ingredients can interfere with each

other and the results could be life threatening and even fatal.

There exists online databases, however, where patients can identify the active ingredients in the drugs

they are taking as well as their interactions in order to prevent negative results.

About the Author



Be the first to comment!

Leave a Response